2022 CAP Congress / Congrès de l'ACP 2022

Session

M3-3 Molecular and Soft Matter Biophysics (DPMB/DCMMP) | Biophysique moléculaire et de la matière molle (DPMB/DPMCM)

M3-3

6 Jun 2022, 16:00

McMaster University

Conveners

M3-3 Molecular and Soft Matter Biophysics (DPMB/DCMMP) | Biophysique moléculaire et de la matière molle (DPMB/DPMCM)

• Cornelia Hoehr

3430. (I) Learning from Life: Understanding and Design of Complex Biophysical Systems through Multiscale Modeling and Machine Learning

Prof. Re Mansbach (Concordia University)

06/06/2022, 16:00

Condensed Matter and Materials Physics / Physique de la matière condensée et matériaux (DCMMP-DPMCM)

Invited Speaker / Conférencier(ère) invité(e)

In recent years, the drug discovery industry has seen a steady decline in productivity due partially to the difficulty in rationally designing and exploring novel search spaces. At the same time, cutting-edge deep learning techniques offer the possibility of rapidly enhancing design of novel biomolecules, but suffer from a lack of interpretability. By employing physics-based techniques,...

3135. The electrostatic gating of carbon nanotube field-effect biosensors characterized at the molecular scale using simulations

Sebastien Cote

06/06/2022, 16:30

Physics in Medicine and Biology / Physique en médecine et en biologie (DPMB-DPMB)

Oral (Non-Student) / Orale (non-étudiant(e))

Carbon nanotube field-effect biosensors (CNT-bioFETs) are ultraminiaturized devices that can be used to measure single-molecule kinetics of biomolecules. They monitor time scales going from a few microseconds to several minutes, as demonstrated for nucleic acid folding and enzyme function. The sensitivity of CNT-bioFETs originates from the interplay between the nanotube’s conductance, which is...

3297. Bringing a Compact Accelerator-based Neutron Source (CANS) to Canada

Drew Marquardt

06/06/2022, 16:45

Condensed Matter and Materials Physics / Physique de la matière condensée et matériaux (DCMMP-DPMCM)

Oral (Non-Student) / Orale (non-étudiant(e))

In response to the retirement of the NRU Reactor at Chalk River Laboratories, a group of Canadian neutron scatterers, cancer clinicians and researchers, and accelerator physicists are carrying out an initial design of a prototype Canadian compact accelerator-based neutron source (PC-CANS) in Canada. The PC-CANS will help mitigate the challenges to maintain and expand the scientific resources...

3420. WITHDRAWN (I) Fabrication of porous bioadhesives via liquid-liquid phase separation of multiprotein condensates

Prof. Matthew Harrington (Dept. of Chemistry, McGill University)

Condensed Matter and Materials Physics / Physique de la matière condensée et matériaux (DCMMP-DPMCM)

Invited Speaker / Conférencier(ère) invité(e)

Wet adhesion is critical for many engineering, biomedical and dental applications; yet, current man-made glues and cements are ineffective on wet surfaces. Mussels, however, can glue themselves firmly on seashore surfaces using protein-based fibers known as byssal threads, each of which terminates in a small adhesive plaque. The byssal plaque is an important role model for understanding...