Speaker
Description
Acoustic computed tomography (ACT) driven by x-ray radiation has gained increasing attention in recent years in the medical imaging community. In a proof-of-concept experiment, relativistic electrons (RE) produced by laser wakefield acceleration were used directly to generate acoustic signals in bovine bone, resulting in its successful structural reconstruction (see companion poster by A. Altamirano et al.). Motivated by this result, we conduct a simulation study to evaluate how various beam parameters, sensor geometries, and sample placements influence reconstruction quality. We also investigate whether sample material properties (e.g. bone density) can be extracted from Fourier analysis of the thermoacoustic response to electron irradiation. Finally, we investigate the potential of these signals to provide in-situ dosimetry during VHEE therapy. Together, these findings highlight the potential of relativistic electron ACT (REACT) as a diagnostic tool for bone diseases such as osteoporosis.
| Working group | WG6 |
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