26th Australian Institute of Physics Congress and the Australian and New Zealand Conference on Optics and Photonics

Session

ANZCOP: Nanophotonics Biosensing

ANZCOP

8 Dec 2026, 16:30

Belinda Hutchinson Building (The University of Sydney )

519. Transforming Tiny Microscale Lasers into Smart Biomedical Sensors

Yu-Cheng Chen (Nanyang Technological University)

08/12/2026, 16:30

ANZOS | Photonics and Optics (ANZCOP)

Invited talk

Lasers are ubiquitous in our daily lives from industry, communication to medicine. The scale of lasers has also shrunk down to micron and nanoscales. As the scale of laser become smaller, the functions of lasers have also been redefined by transforming living biologicals into micro- and nanoscale lasers, so called living lasers. Such tiny lasers could therefore be used to detect or monitor...

796. Selective Photon Collection Enhances Depth-Resolved Contrast

Prof. Alexandre Douplik (Toronto Metropolitan University)

08/12/2026, 17:00

ANZOS | Photonics and Optics (ANZCOP)

Contributed Oral

High-resolution optical imaging in biological tissues is fundamentally limited by photon scattering, which reduces interrogation depth and degrades spatial resolution and absorption-based contrast. Existing scatter-rejection techniques often require complex instrumentation or compromise imaging performance. This study investigates numerical aperture (NA) gating, based on spatial-angular...

680. Optimising Repetition Rate in Two-Photon Light-Sheet Fluorescence Microscopy for Enhanced Signal Efficiency and Reduced Photodamage

Bailey Hoare (Adelaide University)

08/12/2026, 17:15

ANZOS | Photonics and Optics (ANZCOP)

Contributed Oral

Two-photon light-sheet fluorescence microscopy (2P-LSFM) enables rapid volumetric imaging with excellent optical sectioning and deep tissue penetration. Most 2P-LSFM systems use excitation sources at ~80 MHz; however, given the finite fluorescence lifetime of common fluorophores, lower repetition rates may improve signal generation by concentrating the same average power into fewer,...

414. Miniaturised 3D-printed Dual-fibre Optical Coherence Tomography Probe

Yujia Kong

08/12/2026, 17:30

ANZOS | Photonics and Optics (ANZCOP)

Contributed Oral

Optical coherence tomography (OCT) has been widely utilised for biomedical imaging since its early clinical use for retinal microstructural imaging[1]. It has subsequently become a versatile to a broad range of applications, such as cardiology and oncology[2]. This widespread adoption is largely due to OCT’s ability to provide non-invasive, depth-resolved images of tissue structures. However,...

646. Probing Structural Order in p53 Aggregates by Second Harmonic Generation

Yunqian Zou (RMIT, University of Lyon 1)

08/12/2026, 17:45

ANZOS | Photonics and Optics (ANZCOP)

Contributed Oral

Understanding protein structure is essential for elucidating disease mechanisms such as cancer, Alzheimer's disease, and type II diabetes. Among these proteins, the tumor suppressor p53 is particularly critical: its inactivation or mutation occurs in approximately 50% of human cancers. Functioning as a tetramer, p53 regulates DNA repair, cell-cycle arrest, and apoptosis—processes that maintain...