Description
Cell functionality is an active area of research, but many challenges arise due to the complexity of the processes involved. While techniques that provide information about the mechanical properties and/or dynamics of cells exist, they often rely on single point measurements or have limited acquisition speed. To overcome these limitations, I introduce the Rheoscat microscope. This system uses random motion of cells to extract information about intracellular dynamics by illuminating the cell with a 780 nm laser and analysing the fluctuations in the scattering signal. The system was successful in detecting motion reduction in cells treated with PFA compared to healthy cells.
| I am the presenting author | Yes |
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Authors
Daniel Yan
Marino Lara Alva
Dr
Nicolas P. Mauranyapin
(QUBIC)
Prof.
Rohan Teasdale
Prof.
Warwick Bowen
(QUBIC)
Prof.
Yun Chen
Dr
Zhe Yang