2026 CAP Congress / Congrès de l'ACP 2026

Session

(DPMB T2-11 | (DPMB)

T2-11

23 Jun 2026, 14:15

U. Ottawa - Learning Crossroads (CRX) Building

599. Microfluidic High-Throughput Production of Mondisperse Encapsulated Cellular Spheroids

Nicholas Soucy (University of Ottawa)

23/06/2026, 14:15

Oral Competition (Graduate Student) / Compétition orale (Étudiant(e) du 2e ou 3e cycle)

Our work involves the formation and utilization of mass produced, monodisperse spheroids encapsulated in hollow hydrogel microcapsules for use in assays and drug response trials.
Three-dimensional culture of cells into spheroids and organoids shows improved therapeutic and clinical relevance over two-dimensional culture. Heterogeneity of spheroids in size and structure is an issue for...

600. Microfluidic sample compartmentalization for biomolecular concentration quantification using a nanopore sensor

Morteza Safari (University of Ottawa)

23/06/2026, 14:30

Physics in Medicine and Biology / Physique en médecine et en biologie (DPMB-DPMB)

Oral Competition (Graduate Student) / Compétition orale (Étudiant(e) du 2e ou 3e cycle)

Determination of the concentration and physical characteristics of a biomolecule with single molecule sensitivity is a fundamental measurement in biophysics, analytical chemistry, and central to diagnostic applications. In this work, we introduce a microfluidic device with an integrated nanopore sensor, which leverages sample compartmentalization in known pL volumes allowing direct molecular...

770. Effects of macromolecular crowding on protein fold switching

Prof. Stefan Wallin (Memorial University of Newfoundland)

23/06/2026, 14:45

Physics in Medicine and Biology / Physique en médecine et en biologie (DPMB-DPMB)

Oral (Non-Student) / Orale (non-étudiant(e))

While most folded proteins adopt a single, conformationally homogeneous native state, a small but growing class of proteins is known to reversibly switch between two structurally distinct folds. These fold transitions are typically triggered by changes in the local environment, such as binding to a partner molecule or variations in salt concentration or temperature, and often enable new,...

803. Listening to Proteins: How pH Rewrites the Mechanical Language of Elastin Like Materials

Dr Nisha Agarwal (Ontario Tech University)

23/06/2026, 15:15

Physics in Medicine and Biology / Physique en médecine et en biologie (DPMB-DPMB)

Oral (Non-Student) / Orale (non-étudiant(e))

Elastin like polypeptides (ELPs) are remarkable biomaterials. They behave like living systems, constantly reorganizing themselves in response to their environment. Among the many cues that shape their behavior, pH is one of the most powerful, yet one of the least understood at the nanoscale. In this talk, I explore how subtle shifts in acidity rewrite the structural and mechanical “grammar” of...