Conveners
(DPMB) M3-8 Emergent Biological Behaviour I: Molecular Self-Organization to Collective Social Dynamics | Comportements biologiques émergents I: de l'auto-organisation moléculaire aux dynamiques sociales collectives (DPMB)
- Stefan Wallin (Department of Physics and Physical Oceanography, Memorial University of Newfoundland and Labrador, St. John’s, NL, Canada A1B 3X7)
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Francis Dominie22/06/2026, 16:15Physics in Medicine and Biology / Physique en médecine et en biologie (DPMB-DPMB)Oral Competition (Undergraduate Student) / Compétition orale (Étudiant(e) du 1er cycle)
Cellular interiors are densely crowded with proteins and other macromolecules, leading to excluded-volume and weak enthalpic effects that can strongly modulate protein folding, binding, and aggregation. To study these phenomena, we are developing a combined computational-experimental framework to quantify crowding effects using a well-defined “model cytosol” and a sequence-aware coarse-grained...
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Jorja Pevie (Memorial University of Newfoundland)22/06/2026, 16:30Physics in Medicine and Biology / Physique en médecine et en biologie (DPMB-DPMB)Oral Competition (Undergraduate Student) / Compétition orale (Étudiant(e) du 1er cycle)
The interior of cells is a highly dense space in which macromolecules occupy a substantial fraction of the volume. Crowding effects have been shown to impact the conformations and diffusion of proteins, including polymer-like intrinsically disordered proteins. Here we study macromolecular crowding effects in a polymer system consisting of polyethylene glycol (PEG) and Ficoll, which acts as a...
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Ken Tse Pen Ki22/06/2026, 16:45Physics in Medicine and Biology / Physique en médecine et en biologie (DPMB-DPMB)Oral Competition (Undergraduate Student) / Compétition orale (Étudiant(e) du 1er cycle)
Metamorphic proteins are an unusual class of proteins capable of adopting more than one stable native fold, challenging the classical assumption that a single amino acid sequence encodes a single structure. In this work, we investigate the folding behaviour of three closely related proteins: B4, SB3, and the engineered mutant SB4. Despite differing by only a small number of residues, these...
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Marlyn Mwita (University of Waterloo)22/06/2026, 17:00Physics in Medicine and Biology / Physique en médecine et en biologie (DPMB-DPMB)Oral Competition (Graduate Student) / Compétition orale (Étudiant(e) du 2e ou 3e cycle)
Simulating simplified models of social interactions with agent-based models (ABMs) fills a special role in the study of social phenomena, where it is often impossible to design controlled experiments. Schelling’s model of segregation is one of the best-known ABMs, notable for being among the first and simplest to demonstrate how societal outcomes can collectively fail to match individual...
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Bae-Yeun Ha22/06/2026, 17:15Physics in Medicine and Biology / Physique en médecine et en biologie (DPMB-DPMB)Oral (Non-Student) / Orale (non-étudiant(e))
Cells organize their chromosomes through the coordinated action of chromosome-associated proteins and surrounding molecular crowders. In crowded environments, polymeric chains such as chromosomes can undergo entropically driven condensation. Using a coarse-grained computational model, we examine the physical roles of the cross-linking protein H-NS and crowders in bacterial chromosome...
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