Speaker
Description
Microspectrophotometry (MSP), which integrates microscopic imaging with spectrophotometric analysis, is a powerful technique for concurrent morphological and spectral characterization of samples at the micron scale, supporting critical applications in biological sciences, forensic investigations, and materials research. However, the high cost and operational complexity of conventional MSP systems limit their accessibility, particularly in resource-limited environments. In this work, we present a fully standalone, user-friendly, and low-cost MSP system developed on a smartphone platform. The device uniquely leverages both the front and rear cameras of the smartphone, coupled with simple optical components, to simultaneously acquire microscopic images and spectroscopic data from the same sample region, without dependance on external microscopy or spectrometry modules. Compact, lightweight, and enclosed in a 3D-printed housing, the system is constructed entirely from off-the-shelf optoelectronic components. Its performance was validated through imaging and spectral analysis of biological samples, with results benchmarked against a standard laboratory-grade MSP instrument. This smartphone-based MSP system represents an affordable, robust, and practical alternative to conventional systems, expanding access to integrated morphological and spectroscopic analysis for diverse point-of-care and field applications.