Speaker
Description
Since the dawn of the chirped-pulse era [1], rotational spectroscopy emerged as an outstanding tool for structure-solving, enabling novel exploratory approaches with unprecedented tracing capabilities [2]. The enhanced sensitivity and broadband capabilities of chirped-pulse microwave spectroscopy unlocked investigations into increasingly intricate molecular species [3], including notable examples such as artificial molecular motors [4]. Leveraging the inherently narrow line widths of rotational transitions, microwave spectra are unique molecular fingerprints, facilitating unambiguous determination of precise three-dimensional structures and even enabling identification and quantification of enantiomers through recently developed strategies [5,6]. In this contribution, we will discuss recent findings showcasing the wide-ranging applications of broadband rotational spectroscopy, in the realm of molecular structure elucidation and beyond.
References
[1] G. G. Brown, B. C. Dian, K. O. Douglass, S. M. Geyer, S. T. Shipman, B. H. Pate, Rev. Sci. Instrum. 2008, 79, 053103.
[2] S. R. Domingos, C. Pérez, M. Schnell. Annu. Rev. Phys. Chem. 2018, 69, 499-519.
[3] S. R. Domingos, C. Pérez, N. M. Kreienborg, C. Merten, M. Schnell. Commun. Chem. 2021, 4, 32.
[4] S. R. Domingos, A. Cnossen, W. J. Buma, W. R. Browne, B. L. Feringa, M. Schnell, Angew. Chem. Int. Ed. 2017, 56, 11209-11212.
[5] D. Patterson, M. Schnell, J. M. Doyle. Nature 2013, 497, 475-477.
[6] B. H. Pate, L. Evangelisti, W. Caminati, Y. Xu, J. Thomas, D. Patterson, C. Pérez, M. Schnell. Chiral Analysis, Elsevier, 2018, 679-729.
