In underserved regions, infants face heightened risks of brain injury due to the prevalence of adverse factors like infections and malnutrition, compounded by the absence of suitable monitoring tools. Detecting early signs of neonatal brain injury through monitoring cerebral blood oxygenation offers hope in addressing this critical need for underserved communities [1]. The goal of this project...
A novel hand-held point-of-care technology has been developed for “on-farm” detection of pathogens, using the well-established loop-mediated isothermal amplification (LAMP) assay for replicating DNA at constant temperature. The technology uses off-the-shelf primer sets and either a fluorescent DNA binding dye or a fluorescently-labelled DNA probe as the reporter system. LAMP, first described...
Rapid, reliable, specific and sensitive detection of biomolecules are the four pillars of developing sensors especially for point-of-care devices where quick diagnostic times are key to providing first-aid, surgical interventions or emergency treatment. In my talk, I will discuss how sensing starting from simple molecules to complex biomolecules has been achieved in my group. We aim at...
Introduction: Malaria is a blood-borne parasitic disease with an estimated 247 million new cases and 619,000 deaths worldwide in 2021. While this represents a staggering problem at the global-health level, it is tragic among children under the age of five in sub-Saharan Africa where it is the number one cause of death. Even when treatments are available, they are less effective if not...
