2024 CAP Congress / Congrès de l'ACP 2024

Session

(DPMB/DAPI) W2-6 Medical Imaging II | Imagerie médicale II (DPMB/DPAE)

W2-6

29 May 2024, 10:30

Western University

4113. (G) A Novel Estimate of the Positron Displacement on Image Resolution in Quantitative Nuclear Medicine

Philippe Laporte

29/05/2024, 10:30

Symposia Day (DPMB/DAPI - DPMB/DPAI) - Medical Imaging / Imagerie médicale

Oral not-in-competition (Graduate Student) / Orale non-compétitive (Étudiant(e) du 2e ou 3e cycle)

Purpose: In quantitative nuclear medicine, the displacement of the positron before annihilation induces a loss of spatial resolution. As the size of the detectors decreases, this effect becomes non-negligible. In this presentation, I shall address a method of quantifying the displacement of the positron, especially its impacts on the segmentations in dynamic acquisitions. This method takes...

4092. (G*) Investigating the spatiotemporal neuroinflammatory response of half-brain irradiation in a murine model using 18F-FEPPA PET

Sawyer Badiuk (Department of Medical Biophysics at Western University)

29/05/2024, 10:45

Symposia Day (DPMB/DAPI - DPMB/DPAI) - Medical Imaging / Imagerie médicale

Oral Competition (Graduate Student) / Compétition orale (Étudiant(e) du 2e ou 3e cycle)

Brain metastases have been effectively treated with stereotactic radiosurgery (SRS) delivered to visible growths followed by whole brain radiotherapy (WBRT) for microscopic disease. SRS alone is the preferred treatment despite high recurrence, as conventional WBRT is associated with increased cognitive decline. With improved systemic treatments breast cancer patients are living longer...

4211. (G*) Magnetic Particle Imaging can be used for in vivo assessment of the breast tumour microenvironment

Nitara Fernando (Western University)

29/05/2024, 11:00

Symposia Day (DPMB/DAPI - DPMB/DPAI) - Medical Imaging / Imagerie médicale

Oral Competition (Graduate Student) / Compétition orale (Étudiant(e) du 2e ou 3e cycle)

Tumour associated macrophages (TAMs) constitute up to 50% of the breast cancer microenvironment and are linked to adverse patient outcomes. Conventionally, TAM density is assessed through immunohistochemistry (IHC); however, this relies on invasive biopsies and is not representative of the entire tumour. Thus, there is a need for non-invasive, quantitative imaging for in vivo TAM assessment....

4547. Revealing cellular characteristics of the brain in vivo using magnetic resonance imaging

Corey Baron

29/05/2024, 11:15

Physics in Medicine and Biology / Physique en médecine et en biologie (DPMB-DPMB)

Invited Speaker / Conférencier(ère) invité(e)

Magnetic resonance imaging generates image contrast via interactions between the nuclear magnetic moment of atoms and applied magnetic fields. Hydrogen has a non-zero magnetic moment and is abundant in the water within human tissue, making it the predominant source of signal in MRI. Moreover, the active nature of MRI, where the spins are “excited” and then the magnetic fields they emit are...

4491. (G) Sodium (23Na) magnetic resonance imaging (MRI) of prostate cancer using an external coil

Josephine Tan (Western University)

29/05/2024, 11:45

Physics in Medicine and Biology / Physique en médecine et en biologie (DPMB-DPMB)

Oral not-in-competition (Graduate Student) / Orale non-compétitive (Étudiant(e) du 2e ou 3e cycle)

Background
Sodium (23Na) magnetic resonance imaging (MRI) can detect the increased tissue sodium concentration (TSC) exhibited in several tumour types. For prostate cancer imaging, 23Na MRI is conventionally performed using an endorectal coil which is associated with a nonuniform sensitivity profile and limited field of view, constraining its clinical utility. To address these challenges,...