2024 CAP Congress / Congrès de l'ACP 2024

Session

(DPMB) R2-3 Radiation dosimetry, neuron plasticity, muscle branching | Dosimétrie des rayonnements, plasticité des neurones, ramification musculaire (DPMB)

R2-3

30 May 2024, 14:15

Western University

4363. (UG) Comparing the Dose to Circulating Lymphocytes in Conventional and State-of-the-Art Radiation Therapy

Alasdair Holmes (TRIUMF/The University of Edinburgh)

30/05/2024, 14:15

Symposia Day (DPMB/DAPI - DPMB/DPAI) - Medical Imaging / Imagerie médicale

Oral not-in-competition (Undergraduate Student) / Orale non-compétitive (Étudiant(e) du 1er cycle)

Cancer radiotherapy often lowers patients' lymphocyte counts. This radiation induced lymphopenia is significantly correlated with survival for certain treatment sites and cancer types. Despite this, the dose to lymphocytes is not explicitly minimised during clinical treatment planning.

Across patients, a given treatment modality, such as photon or proton therapy (PT), may not...

4626. (G) Exploring the relationship between glucose metabolism and intrinsic functional connectivity in behavioral variant frontotemporal dementia using hybrid PET/MRI

Mathew Joshy (Department of Medical Biophysics, Western University, London, ON)

30/05/2024, 14:30

Symposia Day (DPMB/DAPI - DPMB/DPAI) - Medical Imaging / Imagerie médicale

Oral not-in-competition (Graduate Student) / Orale non-compétitive (Étudiant(e) du 2e ou 3e cycle)

Functional connectivity (FC) has a high energetic demand as demonstrated by hybrid [18F]-Flurodeoxyglucose (FDG) PET and resting state functional MRI (rsfMRI) studies (Tomasi et al., 2013). Regional Homogeneity (ReHo), a rsfMRI local connectivity metric, displays the strongest correlation with metabolism in healthy brain (Aiello et al.,2015), which is reduced in Alzheimer's (AD), potentially...

4509. (UG) Assessing indocyanine green as a chromophore for near-infrared spectroscopy tissue-mimicking phantoms

Redwan Haque (Western University), Rasa Eskandari (Western University)

30/05/2024, 15:00

Symposia Day (DPMB/DAPI - DPMB/DPAI) - Medical Imaging / Imagerie médicale

Oral not-in-competition (Undergraduate Student) / Orale non-compétitive (Étudiant(e) du 1er cycle)

Near-infrared spectroscopy (NIRS) is a non-invasive tool used to assess cerebral health by estimating tissue blood content and oxygenation from measurements of light absorption. To evaluate the accuracy of NIRS devices and algorithms, tissue-mimicking phantoms (TMPs) are used. TMPs typically consist of light-scattering media and light-absorbing dyes, such as Intralipid and indocyanine green...

4157. (G) A Constrained Constructive Optimization Model of Branching Arteriolar Networks in Rat Skeletal Muscle

Yuki Bao (University of Western Ontario)

30/05/2024, 15:15

Physics in Medicine and Biology / Physique en médecine et en biologie (DPMB-DPMB)

Oral not-in-competition (Graduate Student) / Orale non-compétitive (Étudiant(e) du 2e ou 3e cycle)

At the organ and tissue level, the circulation relies on branching networks of microvessels to supply oxygen and other nutrients to all cells in support of metabolism, as well as remove metabolic waste, and derangement of the structure or function of these networks is directly linked to tissue dysfunction. Over a wide range of diameters, these networks are binary trees and display distinct...

4269. (UG) How Proton Therapy and Photon Therapy Affect Secondary Cancer Rates.

Peter Dasiukevich

30/05/2024, 15:30

Symposia Day (DPMB/DAPI - DPMB/DPAI) - Medical Imaging / Imagerie médicale

Oral not-in-competition (Undergraduate Student) / Orale non-compétitive (Étudiant(e) du 1er cycle)

With external beam radiotherapy being a key tool in treating cancer, the possible harmful side effects, e.g. secondary cancer, need to be accounted for and hopefully minimized. As proton therapy (PT) typically spares more healthy tissue than photon therapy, PT may potentially lower the rate of secondary cancers in treated patients. Due to a lack of valid patient data, simulations are required...