2023 CAP Congress / Congrès de l'ACP 2023

Session

(DPMB/DCMMP) T1-1 Soft Matter and Biological Physics Symposium | Symposium sur la matière molle et la physique biologique (DPMB/DPMCM)

T1-1

20 Jun 2023, 08:30

University of New Brunswick

Conveners

(DPMB/DCMMP) T1-1 Soft Matter and Biological Physics Symposium | Symposium sur la matière molle et la physique biologique (DPMB/DPMCM)

• Cornelia Hoehr
• Mamadou Diop (Western University & The Lawson Health Research Institute)
• Robert Wickham
• Maria Kilfoil (University of Prince Edward Island / Physics)
• Valerie Booth
• Melanie Campbell

Description

Session I: Biopolymers in Confined Environments

3939. Single-molecule microscopy of RNA-lipid-nanoparticles: applying nanoscale physics to advance nanomedicines

Sabrina Leslie (UBC Physics and Astronomy and Michael Smith Labs)

20/06/2023, 08:30

Physics in Medicine and Biology / Physique en médecine et en biologie (DPMB-DPMB)

Invited Speaker / Conférencier(ère) invité(e)

I will present a unique quantitative single-molecule imaging platform called CLiC (Convex Lens-induced Confinement) which enables simultaneous measurements of the size, mRNA-payload, and dynamic properties of mRNA-based therapies and vaccines in controlled, cell-like conditions (Kamanzi et al, ACS Nano 2021). Here, we apply single-molecule biophysics to help characterize and understand the...

3884. (G*) Field-Driven Polymer Collisions in Nanotubes

Han yang Wang

20/06/2023, 09:15

Symposia Day (DPMB/DCMMP - DPMB/DPMCM) - Soft Matter and Biological and Physics | Matière molle et physique biologique

Oral Competition (Graduate Student) / Compétition orale (Étudiant(e) du 2e ou 3e cycle)

Even though dilute (unentangled) polymer solutions cannot act as gel-like sieving media, it has been shown that they can be used to separate DNA molecules in capillary electrophoresis. The separation then comes from sporadic and independent polyelectrolyte-polymer collisions. Here we explore such collisions in nanochannels (i.e., channels that are smaller than the normal size of the polymers),...

3837. (I) Polymers under extreme confinement: Insights from computer simulations

James Polson

20/06/2023, 09:30

Symposia Day (DPMB/DCMMP - DPMB/DPMCM) - Soft Matter and Biological and Physics | Matière molle et physique biologique

Invited Speaker / Conférencier(ère) invité(e)

In recent years, nanofluidic devices have proven extremely useful for characterizing the physical behaviour of biopolymers such as DNA confined to narrow channels and micron-sized cavities. Insight gleaned from experiments using nanochannels is valuable for applications such as optical mapping of elongated DNA. Likewise, studies of multiple DNA molecules in nanocavities have provided insight...