2016 CAP Congress / Congrès de l'ACP 2016

Session

M2-2 Molecular Biophysics (DPMB) / Biophysique moléculaire (DPMB)

M2-2

13 Jun 2016, 13:00

University of Ottawa

Conveners

M2-2 Molecular Biophysics (DPMB) / Biophysique moléculaire (DPMB)

• Francis Lin (University of Manitoba)

1286. Femtomedicine in Cancer: Discovery of New Antitumor Molecules for Natural Targeted Chemotherapy and Radiotherapy of Cancers

Prof. Qing-Bin Lu (University of Waterloo)

13/06/2016, 13:00

Physics in Medicine and Biology / Physique en médecine et en biologie (DPMB-DPMB)

Invited Speaker / Conférencier invité

The conquest of cancer continues to pose great challenges to medical science. There is a compelling need for innovative cancer research integrating biomedical sciences with physical sciences in order to ultimately conquer cancer. Femtomedicine (FMD), which integrates femtosecond time-resolved laser spectroscopy with biomedical sciences, was recently coined to advance fundamental understanding...

1121. Observation of coupling between microscopic diffusion and macroscopic elasticity in soft matter

tigran galstian (Laval University)

13/06/2016, 13:30

Physics in Medicine and Biology / Physique en médecine et en biologie (DPMB-DPMB)

Oral (Non-Student) / orale (non-étudiant)

Material diffusion processes are fundamentally driven by local microscopic interactions. Many important applications of diffusion, including drug delivery, are based on this concept. However, some orientational microscopic interactions can generate a collective macroscopic organization. Thus, macroscopic boundary conditions may affect the microscopic diffusion if orientational interactions are...

1184. The Lipid Bilayer Provides a Site for Cortisone Crystallization at High Cortisone Concentrations

Adree Khondker (McMaster University)

13/06/2016, 13:45

Physics in Medicine and Biology / Physique en médecine et en biologie (DPMB-DPMB)

Oral (Student, In Competition) / Orale (Étudiant(e), inscrit à la compétition)

Cortisone is an injected anti-inflammatory drug that is used to treat inflammation. Cortisone’s mechanism of action involves binding to an intracellular receptor which transduces a biochemical cascade to reduce the production of inflammatory prostaglandins. However, cortisone is known to confer side effects, such as pain, known as a “steroid flare” for which the mechanism is unknown. Using...

1195. Coarse-grained simulations of highly driven DNA translocation from a confining nanotube

David Sean (University of Ottawa)

13/06/2016, 14:00

Physics in Medicine and Biology / Physique en médecine et en biologie (DPMB-DPMB)

Oral (Student, In Competition) / Orale (Étudiant(e), inscrit à la compétition)

Driven DNA translocation through a nanoscopic pore has been the focus of many studies in recent years both due to its importance in biological processes and as a promising new technology to probe single DNA molecules. However, the simple process of driving monodisperse DNA chains through a pore often leads to surprisingly wide distributions of translocation times. In the regime where the...

1196. Organization of Nucleotides in Different Environments: Implications for the Formation of First RNA under Prebiotic Conditions

Sebastian Himbert (Mcmaster University)

13/06/2016, 14:15

Physics in Medicine and Biology / Physique en médecine et en biologie (DPMB-DPMB)

Oral (Student, In Competition) / Orale (Étudiant(e), inscrit à la compétition)

How nucleic acids first assembled and then incorporated into the earliest forms of cellular life 4 billion years ago remains a fundamental question of biology. It is postulated that prior to today's DNA, RNA, and protein-dominated world, RNA was used for genetic storage and as a catalyst for reactions, such as polymerization. RNA is a polymer chain of nucleotides linked to a ribose-phosphate...