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28–31 Oct 2024
Heavy Ion Laboratory, University of Warsaw
Europe/Warsaw timezone

Image reconstruction with proton computed tomography

30 Oct 2024, 09:45
45m
„Aula B” Lecture Room (Heavy Ion Laboratory, University of Warsaw)

„Aula B” Lecture Room

Heavy Ion Laboratory, University of Warsaw

Pasteura 5A, 02-093 Warsaw, Poland

Speaker

Zsofia Jolesz

Description

Proton therapy is one of the most effective treatments for cancer, with radiation treatment planning being a crucial element. While photon CT is commonly used for this purpose, it does not provide sufficiently accurate information about proton range, making proton CT a more suitable option for treatment planning. Due to the Coulomb scattering of protons, a key task is the voxel-level calculation of Relative Stopping Power, which requires accurate handling of proton trajectories. Several algorithms have been developed for this purpose. My research focuses on testing, improving, and optimizing a software package that uses the Richardson-Lucy algorithm, developed within the Bergen Proton-CT Collaboration.

I conducted the necessary simulations using Geant4 and GATE software. The framework employing the Richardson-Lucy algorithm was optimized using appropriate methods to enhance speed and efficiency. I validated the algorithm's performance and image reconstruction across different energy levels and medical imaging phantoms designed to assess system accuracy.

As a result of my work, I successfully optimized the algorithm, significantly reducing computation time. The evaluation of phantom reconstructions confirmed that the algorithm operates with the desired accuracy. My long-term goals include further optimization and ensuring clinical applicability, with a focus on further reducing runtime.

Author

Zsofia Jolesz

Presentation materials