Dynamical description of natural systems has generally focused on fixed points, with saddles and saddle-based phase-space objects such as heteroclinic channels/cycles being central concepts behind the emergence of quasi-stable long transients. Reliable and robust transient dynamics observed for real, inherently noisy systems is, however, not met by saddle-based dynamics, as demonstrated here....
The delicate balance necessary for ensuring reliable segregation of cell lineages is an intriguing problem in developmental biology. For mammals, and specifically for the early mouse embryo, cell fate decisions have been extensively researched, but the underlying mechanisms remain poorly understood. Current theoretical approaches to this problem still primarily rely on deterministic modeling,...