Radioimmunotherapy (RIT) uses monoclonal antibodies to deliver cytocidal radiation to the cells with the high precision. So far this approach has been used successfully in cancer arena. However, the principles of RIT could be applied to other, non-cancerous conditions where the diseased cells express the antigens which distinguish them from the healthy cells. Our laboratory is interested in...
Radiopharmaceutical therapy has demonstrated encouraging clinical results in cancer treatment, which stimulated significant attention from the research community, clinicians, and the industry. The radiopharmaceutical therapy is expected to produce pointed effect on cancer lesions while avoiding toxicity to the healthy organs and tissues, which can result in better tolerability in comparison...
Eastern woodchucks (groundhogs) infected with the Woodchuck Hepatitis Virus are a well-established animal model for interventional human hepatic neoplasm therapies such as embolization. The size of the woodchuck overcomes the geometric constraints on imaging and treatment delivery techniques associated with a murine model, and the viral-induced woodchuck tumors more closely resemble the immune...
X-rays and nuclear radiations have been the tools of medical diagnostics and therapy in addition to diverse applications in agriculture, industry and security. Starting from the early 20th century, the development of particle accelerators of diverse species of higher and higher energies along with nuclear reactors have enriched the nuclear tool chest.
Not only have we been able to take...
