Speaker
Paul François
(McGill Unversity)
Description
Subcellular dynamics emerge from the interactions of molecules of many different types, and it seems a priori hopeless to build predictive theories, similar to what is done in physics. In this talk, I will use the example of early immune detection to (briefly) illustrate how approaches inspired by physics -from phenomenology to coarse graining- allow us to untangle the biological interaction “hairball”. This led us to the discovery of the so-called “adaptive sorting” principle, and to the experimental validation of some of its most counterintuitive aspects (in collaboration with Grégoire Altan-Bonnet, NIH).
