Speaker
Prof.
Russell Jacobs
(Beckman Institute / Caltech Brain Imaging Center)
Description
Like any technology, μMRI and μPET have appropriate and inappropriate uses. I will discuss why one might bother with either; then cover a range of applications: how 3D atlas of mouse and quail can be created from high resolution MR images; delve into how lesions and brain structure changes in mouse models of multiple sclerosis are amenable to study with MRI; describe how statistical parametric mapping (SPM) of multiple MRI brain scans of transgenic mouse models provide information about neuronal circuitry alterations. Monitoring changes in tumor physiology is an important aspect of both clinical and pre-clinical imaging – ADC, DCE and cell tracking work will be discussed. Recording of μPET and μMR images simultaneously is a recent development with a host of uses and abuses – work in mouse models of atherosclerosis and oncology require the sensitivity of μPET and resolution with anatomical context of μMRI.
Author
Prof.
Russell Jacobs
(Beckman Institute / Caltech Brain Imaging Center)
