AIP summer meeting 2025

Session

Focus Session: Frontiers of Medical Physics

4 Dec 2025, 10:40

Hope Theatre (Building 40, Room 153)

Conveners

Focus Session: Frontiers of Medical Physics

• Susanna Guatelli
• James Cayley

Focus Session: Frontiers of Medical Physics

• Susanna Guatelli
• James Cayley

40. Non-Ionising Optical Tomography and Inverse Radon Reconstruction for Imaging Diffuse Environments

Ms Catherine Merx (The University of Newcastle)

04/12/2025, 10:40

Frontiers of medical physics

Contributed Oral

This study presents a novel approach to imaging diffuse environments using non-ionising optical tomography combined with inverse Radon reconstruction techniques. We developed and characterised gelatin-based phantom materials with distinct spectral properties, measured using a CloudSpec spectrophotometer across the 350–850 nm range. These materials simulate biological tissues and enable precise...

110. Development of a GEANT4 dosimetric system for orthovoltage x-ray minibeam radiation therapy clinical trials

Vincent de Rover (University of Wollongong)

04/12/2025, 11:10

Frontiers of medical physics

Contributed Oral

Aims:
Recently the first first-in-human minibeam radiation therapy (MBRT) treatments with an orthovoltage x-ray unit at Mayo Clinic, Rochester, Minnesota was presented. We present the development of a GEANT4-based radiation transport model to simulate the minibeam radiation field produced using a clinical orthovoltage machine.

Materials and Methods:
The full clinical orthovoltage machine...

173. Accelerating Innovation: Strategies for Translating Medical Physics Research into the Clinic

Joel Poder (St. George Hospital Cancer Care entre)

04/12/2025, 11:40

Frontiers of medical physics

Focus session invited talk

Hospital based medical physicists are uniquely positioned at the interface between fundamental research and direct patient benefit. Translating innovations from academia and industry into the hospital setting, however, presents both opportunities and challenges. Translational pathways typically involve the progression of prototypes through feasibility testing, clinical trials, and eventual...

215. Of dogs and humans: Does the number of legs matter in the bench-to bedside translation of spatially fractionated radiotherapy techniques?

Prof. Elisabeth Schueltke (Universitätsmedizin Rostock)

04/12/2025, 12:10

Frontiers of medical physics

Contributed Oral

Of the fundamental components of cancer therapy, radiotherapy is by far the one causing the least ecological foot print, compared to surgery and systemic therapy (chemotherapy, immunotherapy). While radiotherapy is mainly a local therapeutic approach, it can help to significantly reduce the requirement for extensive surgery as well as for the need of systemic therapy. From clinical...

230. Opportunities and Challenges of learning from Medical Imaging Data

Lois Holloway (South Western Sydney Local Health District, Ingham Institute and University of New South Wales)

04/12/2025, 13:40

Frontiers of medical physics

Focus session invited talk

Medical Imaging data provides a wealth of information to the health care pathway including diagnosis, understanding disease extent, prognosis, outcome and follow-up. Medical image data can capture anatomical, biological and physiological information through computed tomography, positron emission tomography, magnetic resonance imaging and other approaches. To use this data effectively for an...

266. From physics to patients: Medical physicists driving improved patient outcomes in radiation oncology

Dr Nick Hardcastle (Peter MacCallum Cancer Care Centre)

04/12/2025, 14:10

Frontiers of medical physics

Focus session invited talk

Radiation oncology is a cornerstone of modern cancer care, with approximately 40% of patients receiving radiotherapy (RT) during their cancer journey. Central to its success is achieving an optimal therapeutic ratio: maximising tumour control while minimising side effects. Radiation oncology is a highly technical field, where new algorithm and hardware advances drive improvements in patient...

252. Systematic benchmarking of Monte Carlo Codes for accelerator-based BNCT neutron production targets

Sherryn MacLeod (University of Wollongong)

04/12/2025, 14:40

Medical Physics

Contributed Oral

Beam‑shaping assembly (BSA) design using Monte Carlo techniques for accelerator‑based boron neutron capture therapy (BNCT) requires accurate modelling of light‑ion reactions on thin or thick targets, which define the neutron source term for subsequent beam shaping. Geant4 11.1.3, PHITS 3.33, FLUKA 4‑4.0 and MCNP 6.3 have been benchmarked for thick‑target neutron yield and spectra from...

158. Development of an optimised method for tracking chemical species in Geant4-DNA enabling in-silico radiobiology in a cosmic radiation environment

Susanna Guatelli

04/12/2025, 14:55

Frontiers of medical physics

Contributed Oral

Modelling the early DNA damage induced by radiation is critical for understanding its biological impact. Radiation traversing a cell induces DNA damage through both physical interactions (direct damage) and chemical interactions of radiochemical species (indirect damage) with the DNA strand. Through the combination of DNA geometry models, physics models and chemical tracking, the early DNA...