30 November 2025 to 5 December 2025
Building 40
Australia/Sydney timezone
AIP Summer Meeting 2025 - University of Wollongong

Quantum-AI Biophotonic Diagnostics for Point-of-Care Brain Tumor Screening

5 Dec 2025, 10:55
15m
Hope Theatre (Building 40)

Hope Theatre

Building 40

University of Wollongong Northfields Avenue Wollongong NSW 2522
Contributed Oral Medical Physics Medical Physics

Speaker

Dr Mansoor Ali Khan (Department of Electrical and Computer Engineering, National University of Singapore, 117575, Singapore)

Description

This talk introduces Quantum-AI Biophotonic Diagnostics for Point-of-Care Brain Tumor Screening, a next-generation framework that unites quantum computing, artificial intelligence, and nanoscale biophotonics to transform biomedical diagnostics. We present an integrated approach for early cancer detection that combines plasmonic biophotonic sensors with a quantum machine learning (QML) pipeline, designed for high-sensitivity, non-invasive detection and classification of brain tumors in a compact point-of-care device.

Our system harnesses spectral data from nanoscale plasmonic biosensors, encoding these features via quantum-enhanced methods into a quantum kernel-based learning model. This platform uses quantum-driven feature encoding to process both spectral and imaging signals, enhancing diagnostic accuracy while reducing computational overhead. The framework’s architecture emphasizes efficiency and portability, enabling real-time analysis suitable for clinical and bedside applications.

We further detail the system’s architecture, simulation fidelity, and early experimental results, which demonstrate promising performance in distinguishing tumor signatures. The multidisciplinary innovation—situating light–matter interactions at the nanoscale in concert with quantum intelligence—opens new opportunities for intelligent diagnostic devices capable of immediate cancer screening. Importantly, the implementation highlights pathways for clinical translation, including integration with existing healthcare workflows, regulatory considerations, and validation methodologies.

By leveraging the synergy of quantum technology, artificial intelligence, and biophotonics, this approach has the potential to reshape the landscape of precision oncology and personalized healthcare. Attendees will gain insights into how quantum-biophotonics convergence can revolutionize diagnostic capabilities, enabling earlier and more reliable detection of brain tumors.

Author

Dr Mansoor Ali Khan (Department of Electrical and Computer Engineering, National University of Singapore, 117575, Singapore)

Co-authors

Prof. Biplab Sikdar (Department of Electrical and Computer Engineering, National University of Singapore, 117575, Singapore) Prof. Muhammad Naveed Aman (School of Computing College of Engineering University of Nebraska, Lincoln, NE 68588, United States)

Presentation materials

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