30 November 2025 to 5 December 2025
Building 40
Australia/Sydney timezone
AIP Summer Meeting 2025 - University of Wollongong

High-fidelity Geant4 simulation of the Elekta Unity MR-LINAC for dose prediction

4 Dec 2025, 16:40
15m
Hope Theatre (Building 40)

Hope Theatre

Building 40

University of Wollongong Northfields Avenue Wollongong NSW 2522
Contributed Oral Medical Physics Medical Physics

Speaker

Christopher White (University of Wollongong)

Description

The Elekta Unity is an MR-LINAC that integrates a 7 MV linear accelerator with a 1.5 T MRI in order to provide adaptive online radiotherapy. Using Geant4 version 11.1 and the EMStandard Option 4 Physics Constructor a highly accurate simulation of the Elekta Unity MR-LINAC was developed to produce patient specific dose maps. These dose maps are utilised for the training of a robust dose prediction machine-learning based model. The simulation contains a full model of the treatment head, including the MLC and jaws, as well as the MR cryostat, treatment couch and anterior coil. Simulation of the treatment head allows for positioning to any gantry angle, and individual leaf and jaw positioning allows for the generation of any beam profile, permitting complete control point replication. A uniform 1.5 T magnetic field is applied to the simulated MRI bore through Geant4’s field manager with the Dormand-Prince 745 Runge-Kutta stepper so that the simulation is capable of accurately modelling the effects of the magnetic field on the dose profile. The X-ray beam was finely tuned by investigating the dose profiles for different electron beam configurations. Simulations of a water phantom and surrounding PMMA walls are used to validate the simulation to experimental measurements at gantry angles of 0 and 270 degrees, performed using different detector types. This paper will show that the simulated dose profiles have very strong agreement with the experimental results, with 100% 2%/2mm gamma pass rates for a variety of field sizes and detector depths, including in the crossplane direction, and mean and maximum relative error of less than 1% for the depth dose profiles.

Author

Christopher White (University of Wollongong)

Co-authors

Prof. Ah Chung Tsoi (University of Wollongong) Anatoly Rosenfeld (University of Wollongong) Dr Brad Oborn (University of Wollongong) David Bolst (University of Wollongong) Mr Jack Humphreys (University of Wollongong) Prof. Markus Hagenbuchner (University of Wollongong) Dr Michael Jameson (Genesis Care) Michael Lerch (University of Wollongong) Stéphanie Corde (Prince of Whale Hospital Sydney) Susanna Guatelli Prof. Tomas Kron (Peter MacCallum Cancer Centre)

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